Cargando…
UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
BACKGROUND: Epithelial ovarian cancer (EOC) is a global health burden, with the poorest five-year survival rate of the gynecological malignancies due to diagnosis at advanced stage and high recurrence rate. Recurrence in EOC is driven by the survival of chemoresistant, stem-like tumor-initiating cel...
Autores principales: | Harrington, Brittney S., Kamdar, Rahul, Ning, Franklin, Korrapati, Soumya, Caminear, Michael W., Hernandez, Lidia F., Butcher, Donna, Edmondson, Elijah F., Traficante, Nadia, Hendley, Joy, Gough, Madeline, Rogers, Rebecca, Lourie, Rohan, Shetty, Jyoti, Tran, Bao, Elloumi, Fathi, Abdelmaksoud, Abdalla, Nag, Madhu Lal, Mazan-Mamczarz, Krystyna, House, Carrie D., Hooper, John D., Annunziata, Christina M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585874/ https://www.ncbi.nlm.nih.gov/pubmed/37858159 http://dx.doi.org/10.1186/s13046-023-02820-z |
Ejemplares similares
-
Disulfiram Transcends ALDH Inhibitory Activity When Targeting Ovarian Cancer Tumor-Initiating Cells
por: Caminear, Michael W., et al.
Publicado: (2022) -
Biallelic mutations in UGDH cause congenital microcephaly
por: Shu, Li, et al.
Publicado: (2023) -
NF-κB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells
por: Kamdar, Rahul D., et al.
Publicado: (2023) -
A structural UGDH variant associated with standard Munchkin cats
por: Struck, Ann-Kathrin, et al.
Publicado: (2020) -
UDP-glucose dehydrogenase (UGDH) in clinical oncology and cancer biology
por: Price, Meghan J., et al.
Publicado: (2023)