Transgenerational inheritance of adrenal steroidogenesis inhibition induced by prenatal dexamethasone exposure and its intrauterine mechanism

BACKGROUND: Adrenal gland is the synthesis and secretion organ of glucocorticoid, which is crucial to fetal development and postnatal fate. Recently, we found that prenatal dexamethasone exposure (PDE) could cause adrenal dysfunction in offspring rats, but its multigenerational genetic effects and r...

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Detalles Bibliográficos
Autores principales: He, Zheng, Zhang, Jinzhi, Chen, Yawen, Ai, Can, Gong, Xiaohan, Xu, Dan, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585925/
https://www.ncbi.nlm.nih.gov/pubmed/37853416
http://dx.doi.org/10.1186/s12964-023-01303-0

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