Targeting RPA promotes autophagic flux and the antitumor response to radiation in nasopharyngeal carcinoma

BACKGROUND: Autophagy is involved in nasopharyngeal carcinoma (NPC) radioresistance. Replication protein A 1 (RPA1) and RPA3, substrates of the RPA complex, are potential therapeutic targets for reversing NPC radioresistance. Nevertheless, the role of RPA in autophagy is not adequately understood. T...

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Detalles Bibliográficos
Autores principales: Feng, Yanchun, Jiang, Yingming, Liu, Jun, Liu, Jiaqi, Shi, Mengchen, Chen, Junxiong, Zhang, Jingdan, Tian, Yu, Yang, Xiangling, Liu, Huanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585929/
https://www.ncbi.nlm.nih.gov/pubmed/37858134
http://dx.doi.org/10.1186/s12967-023-04574-w

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