Synthesis, Antifungal Ergosterol Inhibition, Antibiofilm Activities, and Molecular Docking on β-Tubulin and Sterol 14-Alpha Demethylase along with DFT-Based Quantum Mechanical Calculation of Pyrazole Containing Fused Pyridine–Pyrimidine Derivatives

[Image: see text] Multidrug-resistant fungal infections have become much more common in recent years, especially in immune-compromised patients. Therefore, researchers and pharmaceutical professionals have focused on the development of novel antifungal agents that can tackle the problem of resistanc...

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Detalles Bibliográficos
Autores principales: Desai, Nisheeth C., Khasiya, Ashvinkumar G., Jadeja, Dharmpalsinh J., Monapara, Jahnvi D., Jethawa, Aratiba M., Dave, Bharti P., Sivan, Sree Kanth, Manga, Vijjulatha, Mhaske, Pravin C., Chaudhary, Doongar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586022/
https://www.ncbi.nlm.nih.gov/pubmed/37867649
http://dx.doi.org/10.1021/acsomega.3c01722

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