Complete genome sequences of agricultural azole-resistant Penicillium rubens encoding CYP51A and ERG11 paralogues

Azoles are major antifungals in agriculture and medicine. However, the surge of intrinsic azole resistance is critical for public health. Here, we present the complete long-read sequencing of three azole-resistant Penicillium rubens from food crops. The presence of CYP51A and ERG11 paralogues was co...

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Detalles Bibliográficos
Autores principales: Gauthier, Jeff, Mohammadi, Sima, Huffman, Jesse, Lawal, Opeyemi U., Kukavica-Ibrulj, Irena, Potvin, Marianne, Goodridge, Lawrence, Levesque, Roger C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Genome Sequences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586116/
https://www.ncbi.nlm.nih.gov/pubmed/37655927
http://dx.doi.org/10.1128/MRA.00188-23
Descripción
Sumario:Azoles are major antifungals in agriculture and medicine. However, the surge of intrinsic azole resistance is critical for public health. Here, we present the complete long-read sequencing of three azole-resistant Penicillium rubens from food crops. The presence of CYP51A and ERG11 paralogues was confirmed, as in other azole-resistant P. rubens.

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