Characterization of Structurally Diverse (18)F-Labeled d-TCO Derivatives as a PET Probe for Bioorthogonal Pretargeted Imaging

[Image: see text] Background: The pretargeted imaging strategy using inverse electron demand Diels–Alder (IEDDA) cycloaddition between a trans-cyclooctene (TCO) and tetrazine (Tz) has emerged and rapidly grown as a promising concept to improve radionuclide imaging and therapy in oncology. This strat...

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Autores principales: Adhikari, Karuna, Dewulf, Jonatan, Vangestel, Christel, Van der Veken, Pieter, Stroobants, Sigrid, Elvas, Filipe, Augustyns, Koen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586181/
https://www.ncbi.nlm.nih.gov/pubmed/37867688
http://dx.doi.org/10.1021/acsomega.3c04597

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