Design and Synthesis of Ketenimine Sulfonamide Conjugates through Multicomponent Reactions; A Combined Cytotoxic Analysis and Computational Exploration

[Image: see text] Multicomponent reactions involving zwitterion generated from dimethyl acetylenedicarboxylate, aryl sulfonamide, and isocyanide to generate sulfonamide-conjugated ketenimines is reported. The synthetic strategy adopted is highly atom economical and stereoselective. Ketenimine sulfon...

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Detalles Bibliográficos
Autores principales: Prabhu, Deepak J., Ray, Ujjayinee, Rajeev, Anjaly, Joy, Reshma, George, Abi Thoppilan, George, Jinu, Raghavan, Sathees C., John, Franklin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586297/
https://www.ncbi.nlm.nih.gov/pubmed/37867708
http://dx.doi.org/10.1021/acsomega.3c05816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586297/
https://www.ncbi.nlm.nih.gov/pubmed/37867708
http://dx.doi.org/10.1021/acsomega.3c05816

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