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Identification of a Potential Antimycobacterial Drug Sensitizer Targeting a Flavin-Independent Methylenetetrahydrofolate Reductase

[Image: see text] The increasing antibiotic resistance of Mycobacterium tuberculosis and pathogenic nontuberculosis mycobacteria highlights the urgent need for new prevention and treatment strategies. Recently, the cocrystal structure of a Mycobacterium smegmatis flavin-independent 5,10-methylenetet...

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Detalles Bibliográficos
Autores principales: Li, Jiacong, Nian, Yong, Liu, Jian, Yang, Mingxia, Jin, Yuanling, Kang, Xiaoman, Xu, Haodong, Shang, Zhuo, Lin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586308/
https://www.ncbi.nlm.nih.gov/pubmed/37867661
http://dx.doi.org/10.1021/acsomega.3c05021