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Amphiregulin Induces iNOS and COX-2 Expression through NF-κB and MAPK Signaling in Hepatic Inflammation

BACKGROUND: Inflammation is a major cause of hepatic tissue damage and accelerates the progression of nonalcoholic fatty liver disease (NAFLD). Amphiregulin (AREG), an epidermal growth factor receptor ligand, is associated with human liver cirrhosis and hepatocellular carcinoma. We aimed to investig...

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Detalles Bibliográficos
Autores principales: Heo, Yu Jung, Lee, Nami, Choi, Sung-E., Jeon, Ja Young, Han, Seung Jin, Kim, Dae Jung, Kang, Yup, Lee, Kwan Woo, Kim, Hae Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586434/
https://www.ncbi.nlm.nih.gov/pubmed/37868614
http://dx.doi.org/10.1155/2023/2364121

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