A potential adverse role for leptin and cardiac leptin receptor in the right ventricle in pulmonary arterial hypertension: effect of metformin is BMPR2 mutation-specific

INTRODUCTION: Pulmonary arterial hypertension is a fatal cardiopulmonary disease. Leptin, a neuroendocrine hormone released by adipose tissue, has a complex relationship with cardiovascular diseases, including PAH. Leptin is thought to be an important factor linking metabolic syndrome and cardiovasc...

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Detalles Bibliográficos
Autores principales: Talati, Megha, Brittain, Evan, Agrawal, Vineet, Fortune, Niki, Simon, Katie, Shay, Sheila, Zeng, Xiaofang, Freeman, Michael L., West, James, Hemnes, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586504/
https://www.ncbi.nlm.nih.gov/pubmed/37869164
http://dx.doi.org/10.3389/fmed.2023.1276422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586504/
https://www.ncbi.nlm.nih.gov/pubmed/37869164
http://dx.doi.org/10.3389/fmed.2023.1276422

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