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Gα Protein Signaling Bias at Serotonin 1A Receptor

Serotonin 1A receptor (5-HT1AR) is a clinically relevant target because of its involvement in several central and peripheral functions, including sleep, temperature homeostasis, processing of emotions, and response to stress. As a G protein coupled receptor (GPCR) activating numerous Gα(i/o/z) famil...

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Detalles Bibliográficos
Autores principales: Alabdali, Rana, Franchini, Luca, Orlandi, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586511/
https://www.ncbi.nlm.nih.gov/pubmed/37567783
http://dx.doi.org/10.1124/molpharm.123.000722

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