Cargando…

Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study

Patients on maintenance hemodialysis are at a great risk for altered nutritional status, characterized by protein energy wasting and micronutrient deficiency due to medication interactions and dietary restrictions. This study determined the dietary intake, micronutrient profile and body composition...

Descripción completa

Detalles Bibliográficos
Autores principales: Sembajwe, Fred Lawrence, Namaganda, Agnes, Nfambi, Joshua, Muwonge, Haruna, Katamba, Godfrey, Nakato, Ritah, Nabachenje, Prossy, Kawala Kagoya, Enid, Namubamba, Annet, Kiggundu, Daniel, Bitek, Brian, Kalyesubula, Robert, Iputo, Jehu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586598/
https://www.ncbi.nlm.nih.gov/pubmed/37856499
http://dx.doi.org/10.1371/journal.pone.0291813
_version_ 1785123178001989632
author Sembajwe, Fred Lawrence
Namaganda, Agnes
Nfambi, Joshua
Muwonge, Haruna
Katamba, Godfrey
Nakato, Ritah
Nabachenje, Prossy
Kawala Kagoya, Enid
Namubamba, Annet
Kiggundu, Daniel
Bitek, Brian
Kalyesubula, Robert
Iputo, Jehu
author_facet Sembajwe, Fred Lawrence
Namaganda, Agnes
Nfambi, Joshua
Muwonge, Haruna
Katamba, Godfrey
Nakato, Ritah
Nabachenje, Prossy
Kawala Kagoya, Enid
Namubamba, Annet
Kiggundu, Daniel
Bitek, Brian
Kalyesubula, Robert
Iputo, Jehu
author_sort Sembajwe, Fred Lawrence
collection PubMed
description Patients on maintenance hemodialysis are at a great risk for altered nutritional status, characterized by protein energy wasting and micronutrient deficiency due to medication interactions and dietary restrictions. This study determined the dietary intake, micronutrient profile and body composition of patients on maintenance hemodialysis at Kiruddu National referral hospital (KNRH), Uganda. A cross sectional study was done among adult CKD patients on maintenance hemodialysis therapy at KNRH. Data concerning patients’ demographics, clinical history and dietary intake was obtained using interactive and quantitative food frequency questionnaires. Body composition was obtained using the TANITA BC-351, Japan weighing Bathroom scale and anthropometric measurements using standard methods and procedures. Serum micronutrient profile assessment was done using the COBAS Auto analyzer. Data analysis was done using the SPSS software version 20. T-test was used to make comparisons and logistic regression analysis was done to check for any correlations. A P-value of < 0.05 was considered statistically significant. Among the 63 hemodialysis patients, 38% were female, with a median duration of hemodialysis of 12 months and the overall age range of patients was 31–40 years. Majority (92.1%) of the patients had hypertension. Carbohydrates like maize flour were highly consumed, in addition to eggs among the proteins on the daily basis. Fruits and vegetables were not highly consumed. Regarding body composition; 75% of the study participants had normal Body mass Index (BMI), the mean muscle mass was 51.94±8.68, body fat was 15.25±7.35, bone mass was 2.77±0.46 and body water was 62.04±9.06. Patients had deranged micronutrient levels especially for Vitamin D, Potassium and phosphorus. In conclusion, hemodialysis patients at KNRH, have altered nutritional status as evidenced by altered body weight for some patients and deranged micronutrient levels. We recommend that hemodialysis patients should be regularly assessed for nutritional status, appropriately treated and educated about their nutritional status.
format Online
Article
Text
id pubmed-10586598
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-105865982023-10-20 Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study Sembajwe, Fred Lawrence Namaganda, Agnes Nfambi, Joshua Muwonge, Haruna Katamba, Godfrey Nakato, Ritah Nabachenje, Prossy Kawala Kagoya, Enid Namubamba, Annet Kiggundu, Daniel Bitek, Brian Kalyesubula, Robert Iputo, Jehu PLoS One Research Article Patients on maintenance hemodialysis are at a great risk for altered nutritional status, characterized by protein energy wasting and micronutrient deficiency due to medication interactions and dietary restrictions. This study determined the dietary intake, micronutrient profile and body composition of patients on maintenance hemodialysis at Kiruddu National referral hospital (KNRH), Uganda. A cross sectional study was done among adult CKD patients on maintenance hemodialysis therapy at KNRH. Data concerning patients’ demographics, clinical history and dietary intake was obtained using interactive and quantitative food frequency questionnaires. Body composition was obtained using the TANITA BC-351, Japan weighing Bathroom scale and anthropometric measurements using standard methods and procedures. Serum micronutrient profile assessment was done using the COBAS Auto analyzer. Data analysis was done using the SPSS software version 20. T-test was used to make comparisons and logistic regression analysis was done to check for any correlations. A P-value of < 0.05 was considered statistically significant. Among the 63 hemodialysis patients, 38% were female, with a median duration of hemodialysis of 12 months and the overall age range of patients was 31–40 years. Majority (92.1%) of the patients had hypertension. Carbohydrates like maize flour were highly consumed, in addition to eggs among the proteins on the daily basis. Fruits and vegetables were not highly consumed. Regarding body composition; 75% of the study participants had normal Body mass Index (BMI), the mean muscle mass was 51.94±8.68, body fat was 15.25±7.35, bone mass was 2.77±0.46 and body water was 62.04±9.06. Patients had deranged micronutrient levels especially for Vitamin D, Potassium and phosphorus. In conclusion, hemodialysis patients at KNRH, have altered nutritional status as evidenced by altered body weight for some patients and deranged micronutrient levels. We recommend that hemodialysis patients should be regularly assessed for nutritional status, appropriately treated and educated about their nutritional status. Public Library of Science 2023-10-19 /pmc/articles/PMC10586598/ /pubmed/37856499 http://dx.doi.org/10.1371/journal.pone.0291813 Text en © 2023 Sembajwe et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Sembajwe, Fred Lawrence
Namaganda, Agnes
Nfambi, Joshua
Muwonge, Haruna
Katamba, Godfrey
Nakato, Ritah
Nabachenje, Prossy
Kawala Kagoya, Enid
Namubamba, Annet
Kiggundu, Daniel
Bitek, Brian
Kalyesubula, Robert
Iputo, Jehu
Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title_full Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title_fullStr Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title_full_unstemmed Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title_short Dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending Kiruddu National Referral Hospital, Uganda: A cross sectional study
title_sort dietary intake, body composition and micronutrient profile of patients on maintenance hemodialysis attending kiruddu national referral hospital, uganda: a cross sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586598/
https://www.ncbi.nlm.nih.gov/pubmed/37856499
http://dx.doi.org/10.1371/journal.pone.0291813
work_keys_str_mv AT sembajwefredlawrence dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT namagandaagnes dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT nfambijoshua dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT muwongeharuna dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT katambagodfrey dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT nakatoritah dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT nabachenjeprossy dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT kawalakagoyaenid dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT namubambaannet dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT kiggundudaniel dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT bitekbrian dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT kalyesubularobert dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy
AT iputojehu dietaryintakebodycompositionandmicronutrientprofileofpatientsonmaintenancehemodialysisattendingkiruddunationalreferralhospitalugandaacrosssectionalstudy