Cargando…

Identification of the regulatory circuit governing corneal epithelial fate determination and disease

The transparent corneal epithelium in the eye is maintained through the homeostasis regulated by limbal stem cells (LSCs), while the nontransparent epidermis relies on epidermal keratinocytes for renewal. Despite their cellular similarities, the precise cell fates of these two types of epithelial st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smits, Jos G. A., Cunha, Dulce Lima, Amini, Maryam, Bertolin, Marina, Laberthonnière, Camille, Qu, Jieqiong, Owen, Nicholas, Latta, Lorenz, Seitz, Berthold, Roux, Lauriane N., Stachon, Tanja, Ferrari, Stefano, Moosajee, Mariya, Aberdam, Daniel, Szentmary, Nora, van Heeringen, Simon J., Zhou, Huiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586658/ https://www.ncbi.nlm.nih.gov/pubmed/37856539 http://dx.doi.org/10.1371/journal.pbio.3002336

Ejemplares similares

Hypoxic stress increases NF-κB and iNOS mRNA expression in normal, but not in keratoconus corneal fibroblasts
por: Stachon, Tanja, et al.
Publicado: (2020)

NF-κB, iNOS, IL-6, and collagen 1 and 5 expression in healthy and keratoconus corneal fibroblasts after 0.1% riboflavin UV-A illumination
por: Berger, Tim, et al.
Publicado: (2021)

Keratin 12 mRNA expression could serve as an early corneal marker for limbal explant cultures
por: Shi, Lei, et al.
Publicado: (2020)

Response to: HCE-T cells express cornea-specific differentiation marker, PAX6 protein
por: Latta, Lorenz, et al.
Publicado: (2022)

Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas
por: Stachon, Tanja, et al.
Publicado: (2022)

Single-Cell RNA Sequencing: Opportunities and Challenges for Studies on Corneal Biology in Health and Disease
por: Arts, Julian A., et al.
Publicado: (2023)

Similarities in DSG1 and KRT3 Downregulation through Retinoic Acid Treatment and PAX6 Knockdown Related Expression Profiles: Does PAX6 Affect RA Signaling in Limbal Epithelial Cells?
por: Latta, Lorenz, et al.
Publicado: (2021)

The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro
por: Shi, Lei, et al.
Publicado: (2020)

Vignetting and Field of View with the KAMRA Corneal Inlay
por: Langenbucher, Achim, et al.
Publicado: (2013)

Impact of crosslinking/riboflavin-UVA-photodynamic inactivation on viability, apoptosis and activation of human keratocytes in vitro
por: Stachon, Tanja, et al.
Publicado: (2015)

Viability, Apoptosis, Proliferation, Activation, and Cytokine Secretion of Human Keratoconus Keratocytes after Cross-Linking
por: Song, Xuefei, et al.
Publicado: (2015)

Effect of prolactin on normal and keratoconus human corneal stromal fibroblasts in vitro
por: Anders, Philipp, et al.
Publicado: (2021)

Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs
por: Lima Cunha, Dulce, et al.
Publicado: (2023)

A step closer toward therapies for p63-related disorders
por: Zhou, Huiqing, et al.
Publicado: (2013)

Animal and cellular models of microphthalmia
por: Harding, Philippa, et al.
Publicado: (2021)

Efficacy of Off-Label Anti-Amoebic Agents to Suppress Trophozoite Formation of Acanthamoeba spp. on Non-Nutrient Agar Escherichia Coli Plates
por: Muthukumar, Vithusan, et al.
Publicado: (2022)

The Spectrum of PAX6 Mutations and Genotype-Phenotype Correlations in the Eye
por: Lima Cunha, Dulce, et al.
Publicado: (2019)

Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells
por: Eintracht, Jonathan, et al.
Publicado: (2022)

ANANSE: an enhancer network-based computational approach for predicting key transcription factors in cell fate determination
por: Xu, Quan, et al.
Publicado: (2021)

Eye-Tracker-Guided Non-Mechanical Excimer Laser Assisted Penetrating Keratoplasty
por: Janunts, Edgar, et al.
Publicado: (2013)

Longitudinal genotype-phenotype analysis in 86 patients with PAX6-related aniridia
por: Kit, Vivienne, et al.
Publicado: (2021)

PAX6 disease models for aniridia
por: Abdolkarimi, Dorsa, et al.
Publicado: (2022)

Ausgeprägter Wessely-Immunring bei Keratitis – ein Chamäleon
por: Weinstein, Isabel, et al.
Publicado: (2020)

Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1(MET)/APR-246
por: Aberdam, Edith, et al.
Publicado: (2020)

Corneal epithelial ingrowth after perforating corneal injury: a case report
por: Quintin, Adrien, et al.
Publicado: (2022)

Keratokonusdetektion und Ableitung des Ausprägungsgrades aus den Parametern des Corvis®ST: Eine Studie, basierend auf Algorithmen des Maschinenlernens
por: Langenbucher, Achim, et al.
Publicado: (2020)

Penetrating Keratoplasty for Keratoconus – Excimer Versus Femtosecond Laser Trephination
por: Seitz, Berthold, et al.
Publicado: (2017)

PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism
por: Lima Cunha, Dulce, et al.
Publicado: (2020)

Why the Corvis Biomechanical Factor Should Only Be Used for Corneal Ectasia
por: Herber, Robert, et al.
Publicado: (2023)

Acanthamoeba keratitis – Clinical signs, differential diagnosis and treatment
por: Szentmáry, Nóra, et al.
Publicado: (2018)

Intraocular lens power calculation in eyes with previous corneal refractive surgery
por: Anders, Philipp, et al.
Publicado: (2022)

Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
por: Méjécase, Cécile, et al.
Publicado: (2020)

Generation of human iPSC line (UCLi013-A) from a patient with microphthalmia and aniridia, carrying a heterozygous missense mutation c.372C>A p.(Asn124Lys) in PAX6
por: Harding, Philippa, et al.
Publicado: (2021)

Generation of two human iPSC lines from patients with autosomal dominant retinitis pigmentosa (UCLi014-A) and autosomal recessive Leber congenital amaurosis (UCLi015-A), associated with RDH12 variants
por: Sarkar, Hajrah, et al.
Publicado: (2021)

Prediction of corneal power vectors after cataract surgery with toric lens implantation–A vector analysis
por: Langenbucher, Achim, et al.
Publicado: (2023)

Hypothyroidism is Not Associated with Keratoconus Disease: Analysis of 626 Subjects
por: Flaskó, Zsuzsa, et al.
Publicado: (2019)

COL8A2 Regulates the Fate of Corneal Endothelial Cells
por: Hwang, Jin Sun, et al.
Publicado: (2020)

Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis
por: Li, Mingsen, et al.
Publicado: (2021)

Bootstrapping of Corneal Optical Coherence Tomography Data to Investigate Conic Fit Robustness
por: Langenbucher, Achim, et al.
Publicado: (2023)

The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A
por: Smits, Jos P.H., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qfu4f53uru1e4l64civnl429ps