The associations of alcoholic liver disease and nonalcoholic fatty liver disease with bone mineral density and the mediation of serum 25-Hydroxyvitamin D: A bidirectional and two-step Mendelian randomization

BACKGROUND: Reduced bone mineral density (BMD) and osteoporosis are common in chronic liver diseases. However, the causal effect of alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) on BMD remains uncertain. OBJECTIVES: This study uses a two-sample Mendelian randomization (...

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Detalles Bibliográficos
Autores principales: Huang, Qinyao, Guo, Jianglong, Zhao, Hongjun, Zheng, Yi, Zhang, Yuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586666/
https://www.ncbi.nlm.nih.gov/pubmed/37856513
http://dx.doi.org/10.1371/journal.pone.0292881

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