Cargando…

Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report

Symptoms of COVID-19 infection are usually mild in the healthy pediatric population. In some pediatric patients, COVID-19 infection can lead to multisystem inflammatory syndrome in children (MIS-C). We report two cases. Case 1 is a rare case of MIS-C symptoms, presenting with myalgia, chest pain, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Zapata, Miana R, Pandit, Trupti, Goyal, Lokesh, Ajmera, Kunal, Chourasia, Prabal, Pandit, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586754/
https://www.ncbi.nlm.nih.gov/pubmed/37868506
http://dx.doi.org/10.7759/cureus.45564
_version_ 1785123210451222528
author Zapata, Miana R
Pandit, Trupti
Goyal, Lokesh
Ajmera, Kunal
Chourasia, Prabal
Pandit, Ramesh
author_facet Zapata, Miana R
Pandit, Trupti
Goyal, Lokesh
Ajmera, Kunal
Chourasia, Prabal
Pandit, Ramesh
author_sort Zapata, Miana R
collection PubMed
description Symptoms of COVID-19 infection are usually mild in the healthy pediatric population. In some pediatric patients, COVID-19 infection can lead to multisystem inflammatory syndrome in children (MIS-C). We report two cases. Case 1 is a rare case of MIS-C symptoms, presenting with myalgia, chest pain, and fever three days after the second dose of the Pfizer-BioNTech COVID-19 vaccine, which is compared with Case 2, which is a case of MIS-C in an unvaccinated patient with COVID-19 infection who was noted to have acute kidney injury and fluid refractory hypotension. Although MIS-C was reported as a vaccine side effect, we conclude that COVID-19 infection led to the development of MIS-C in our case, not the COVID-19 vaccine. MIS-C symptoms were also noted to be less severe after the COVID-19 vaccine than in the unvaccinated patients.
format Online
Article
Text
id pubmed-10586754
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-105867542023-10-20 Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report Zapata, Miana R Pandit, Trupti Goyal, Lokesh Ajmera, Kunal Chourasia, Prabal Pandit, Ramesh Cureus Pediatrics Symptoms of COVID-19 infection are usually mild in the healthy pediatric population. In some pediatric patients, COVID-19 infection can lead to multisystem inflammatory syndrome in children (MIS-C). We report two cases. Case 1 is a rare case of MIS-C symptoms, presenting with myalgia, chest pain, and fever three days after the second dose of the Pfizer-BioNTech COVID-19 vaccine, which is compared with Case 2, which is a case of MIS-C in an unvaccinated patient with COVID-19 infection who was noted to have acute kidney injury and fluid refractory hypotension. Although MIS-C was reported as a vaccine side effect, we conclude that COVID-19 infection led to the development of MIS-C in our case, not the COVID-19 vaccine. MIS-C symptoms were also noted to be less severe after the COVID-19 vaccine than in the unvaccinated patients. Cureus 2023-09-19 /pmc/articles/PMC10586754/ /pubmed/37868506 http://dx.doi.org/10.7759/cureus.45564 Text en Copyright © 2023, Zapata et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pediatrics
Zapata, Miana R
Pandit, Trupti
Goyal, Lokesh
Ajmera, Kunal
Chourasia, Prabal
Pandit, Ramesh
Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title_full Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title_fullStr Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title_full_unstemmed Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title_short Multisystem Inflammatory Syndrome Due to COVID-19 Infection in Vaccinated Versus Unvaccinated Adolescents: A Case Report
title_sort multisystem inflammatory syndrome due to covid-19 infection in vaccinated versus unvaccinated adolescents: a case report
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586754/
https://www.ncbi.nlm.nih.gov/pubmed/37868506
http://dx.doi.org/10.7759/cureus.45564
work_keys_str_mv AT zapatamianar multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport
AT pandittrupti multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport
AT goyallokesh multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport
AT ajmerakunal multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport
AT chourasiaprabal multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport
AT panditramesh multisysteminflammatorysyndromeduetocovid19infectioninvaccinatedversusunvaccinatedadolescentsacasereport