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Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia
INTRODUCTION. Medical device colonization by pathogenic microorganisms is a risk factor for increasing infections associated with health care and, consequently, the morbidity and mortality of intubated patients. In Colombia, fungal colonization of endotracheal tubes has not been described, and this...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Nacional de Salud
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586799/ https://www.ncbi.nlm.nih.gov/pubmed/37721909 http://dx.doi.org/10.7705/biomedica.6884 |
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author | Huertas, Mónica Gabriela Rodríguez, Miguel Castro, Patricia Cruz, Sergio Danilo Cifuentes, Érika Alejandra Yepes, Andrés Felipe Zambrano, María Mercedes Baldión, Ana Margarita |
author_facet | Huertas, Mónica Gabriela Rodríguez, Miguel Castro, Patricia Cruz, Sergio Danilo Cifuentes, Érika Alejandra Yepes, Andrés Felipe Zambrano, María Mercedes Baldión, Ana Margarita |
author_sort | Huertas, Mónica Gabriela |
collection | PubMed |
description | INTRODUCTION. Medical device colonization by pathogenic microorganisms is a risk factor for increasing infections associated with health care and, consequently, the morbidity and mortality of intubated patients. In Colombia, fungal colonization of endotracheal tubes has not been described, and this information could lead to new therapeutic options for the benefit of patients. OBJECTIVE. To describe the colonizing fungi of the endotracheal tubes from patients in the intensive care unit, along with its antifungal sensitivity profile. MATERIALS AND METHODS. We conducted a descriptive, observational study in two health centers for 12 months. Endotracheal tubes were collected from patients in intensive care units. Samples were processed for culture, fungi identification, and antifungal sensitivity profile assessment. RESULTS. A total of 121 endotracheal tubes, obtained from 113 patients, were analyzed: 41.32 % of the tubes were colonized by Candida albicans (64.62%), C. non-albicans (30.77%), Cryptococcus spp. (3.08%) or molds (1.54%). All fungi evaluated showed a high sensitivity to antifungals, with a mean of 91%. CONCLUSION. Fungal colonization was found in the endotracheal tubes of patients under invasive mechanical ventilation. The antifungal sensitivity profile in these patients was favorable. A clinical study is required to find possible correlations between the colonizing microorganisms and infectivity. |
format | Online Article Text |
id | pubmed-10586799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Instituto Nacional de Salud |
record_format | MEDLINE/PubMed |
spelling | pubmed-105867992023-10-20 Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia Huertas, Mónica Gabriela Rodríguez, Miguel Castro, Patricia Cruz, Sergio Danilo Cifuentes, Érika Alejandra Yepes, Andrés Felipe Zambrano, María Mercedes Baldión, Ana Margarita Biomedica Artículo Original INTRODUCTION. Medical device colonization by pathogenic microorganisms is a risk factor for increasing infections associated with health care and, consequently, the morbidity and mortality of intubated patients. In Colombia, fungal colonization of endotracheal tubes has not been described, and this information could lead to new therapeutic options for the benefit of patients. OBJECTIVE. To describe the colonizing fungi of the endotracheal tubes from patients in the intensive care unit, along with its antifungal sensitivity profile. MATERIALS AND METHODS. We conducted a descriptive, observational study in two health centers for 12 months. Endotracheal tubes were collected from patients in intensive care units. Samples were processed for culture, fungi identification, and antifungal sensitivity profile assessment. RESULTS. A total of 121 endotracheal tubes, obtained from 113 patients, were analyzed: 41.32 % of the tubes were colonized by Candida albicans (64.62%), C. non-albicans (30.77%), Cryptococcus spp. (3.08%) or molds (1.54%). All fungi evaluated showed a high sensitivity to antifungals, with a mean of 91%. CONCLUSION. Fungal colonization was found in the endotracheal tubes of patients under invasive mechanical ventilation. The antifungal sensitivity profile in these patients was favorable. A clinical study is required to find possible correlations between the colonizing microorganisms and infectivity. Instituto Nacional de Salud 2023-08-31 /pmc/articles/PMC10586799/ /pubmed/37721909 http://dx.doi.org/10.7705/biomedica.6884 Text en https://creativecommons.org/licenses/by/4.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons |
spellingShingle | Artículo Original Huertas, Mónica Gabriela Rodríguez, Miguel Castro, Patricia Cruz, Sergio Danilo Cifuentes, Érika Alejandra Yepes, Andrés Felipe Zambrano, María Mercedes Baldión, Ana Margarita Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title | Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title_full | Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title_fullStr | Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title_full_unstemmed | Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title_short | Descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en Bogotá, Colombia |
title_sort | descripción de la micobiota de los tubos endotraqueales de pacientes de unidades de cuidados intensivos en bogotá, colombia |
topic | Artículo Original |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586799/ https://www.ncbi.nlm.nih.gov/pubmed/37721909 http://dx.doi.org/10.7705/biomedica.6884 |
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