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Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer

PAM50 gene expression subtypes represent a cornerstone in the molecular classification of breast cancer and are included in risk prediction models to guide therapy. We aimed to illustrate the impact of included genes and biological processes on subtyping while considering a tumor’s underlying clinic...

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Detalles Bibliográficos
Autores principales: Veerla, Srinivas, Hohmann, Lennart, Nacer, Deborah F., Vallon-Christersson, Johan, Staaf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587090/
https://www.ncbi.nlm.nih.gov/pubmed/37857634
http://dx.doi.org/10.1038/s41523-023-00589-0