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Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval

Recent research has indicated that the cerebellum is engaged in language functions, yet the role of the cerebellum in lexical-semantic memory is poorly understood. In a double-blind randomized controlled experiment, we therefore targeted the cerebellum by transcranial direct current stimulation (tDC...

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Autores principales: Petríková, Dominika, Marko, Martin, Rovný, Rastislav, Riečanský, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587269/
https://www.ncbi.nlm.nih.gov/pubmed/37783862
http://dx.doi.org/10.1007/s00429-023-02712-0
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author Petríková, Dominika
Marko, Martin
Rovný, Rastislav
Riečanský, Igor
author_facet Petríková, Dominika
Marko, Martin
Rovný, Rastislav
Riečanský, Igor
author_sort Petríková, Dominika
collection PubMed
description Recent research has indicated that the cerebellum is engaged in language functions, yet the role of the cerebellum in lexical-semantic memory is poorly understood. In a double-blind randomized controlled experiment, we therefore targeted the cerebellum by transcranial direct current stimulation (tDCS) to assess and compare the contribution of the cerebellar processing to automatic and controlled retrieval of words in healthy adults (n = 136). Anodal cerebellar tDCS facilitated retrieval of semantically related words in free-associative chains, which was not due to a non-specific acceleration of processing speed. The stimulation had no influence on controlled word retrieval that employed inhibition or switching. The effect of cathodal tDCS was opposite to the anodal stimulation, but statistically non-significant. Our data show that the cerebellum is engaged extracting associative information from the system of semantic representations, established and strengthened/automated by learning, and indicates a domain-general role of this structure in automation of behavior, cognition and language. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00429-023-02712-0.
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spelling pubmed-105872692023-10-21 Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval Petríková, Dominika Marko, Martin Rovný, Rastislav Riečanský, Igor Brain Struct Funct Original Article Recent research has indicated that the cerebellum is engaged in language functions, yet the role of the cerebellum in lexical-semantic memory is poorly understood. In a double-blind randomized controlled experiment, we therefore targeted the cerebellum by transcranial direct current stimulation (tDCS) to assess and compare the contribution of the cerebellar processing to automatic and controlled retrieval of words in healthy adults (n = 136). Anodal cerebellar tDCS facilitated retrieval of semantically related words in free-associative chains, which was not due to a non-specific acceleration of processing speed. The stimulation had no influence on controlled word retrieval that employed inhibition or switching. The effect of cathodal tDCS was opposite to the anodal stimulation, but statistically non-significant. Our data show that the cerebellum is engaged extracting associative information from the system of semantic representations, established and strengthened/automated by learning, and indicates a domain-general role of this structure in automation of behavior, cognition and language. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00429-023-02712-0. Springer Berlin Heidelberg 2023-10-02 2023 /pmc/articles/PMC10587269/ /pubmed/37783862 http://dx.doi.org/10.1007/s00429-023-02712-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Petríková, Dominika
Marko, Martin
Rovný, Rastislav
Riečanský, Igor
Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title_full Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title_fullStr Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title_full_unstemmed Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title_short Electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
title_sort electrical stimulation of the cerebellum facilitates automatic but not controlled word retrieval
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587269/
https://www.ncbi.nlm.nih.gov/pubmed/37783862
http://dx.doi.org/10.1007/s00429-023-02712-0
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