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A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy

Children with cerebral palsy (CP) often show executive function (EF) impairments that are key to quality of life. The aim of this study was to assess whether a home-based computerized intervention program improves executive functions (EFs) compared to usual care. Sixty participants (30 females) with...

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Autores principales: García-Galant, María, Blasco, Montse, Laporta-Hoyos, Olga, Berenguer-González, Alba, Moral-Salicrú, Paula, Ballester-Plané, Júlia, Caldú, Xavier, Miralbell, Júlia, Alonso, Xènia, Medina-Cantillo, Julita, Povedano-Bulló, Elsa, Leiva, David, Boyd, Roslyn N., Pueyo, Roser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587273/
https://www.ncbi.nlm.nih.gov/pubmed/37462799
http://dx.doi.org/10.1007/s00431-023-05072-3
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author García-Galant, María
Blasco, Montse
Laporta-Hoyos, Olga
Berenguer-González, Alba
Moral-Salicrú, Paula
Ballester-Plané, Júlia
Caldú, Xavier
Miralbell, Júlia
Alonso, Xènia
Medina-Cantillo, Julita
Povedano-Bulló, Elsa
Leiva, David
Boyd, Roslyn N.
Pueyo, Roser
author_facet García-Galant, María
Blasco, Montse
Laporta-Hoyos, Olga
Berenguer-González, Alba
Moral-Salicrú, Paula
Ballester-Plané, Júlia
Caldú, Xavier
Miralbell, Júlia
Alonso, Xènia
Medina-Cantillo, Julita
Povedano-Bulló, Elsa
Leiva, David
Boyd, Roslyn N.
Pueyo, Roser
author_sort García-Galant, María
collection PubMed
description Children with cerebral palsy (CP) often show executive function (EF) impairments that are key to quality of life. The aim of this study was to assess whether a home-based computerized intervention program improves executive functions (EFs) compared to usual care. Sixty participants (30 females) with CP (8–12 years old) were paired by age, sex, motor ability, and intelligence quotient score and then randomized to intervention and waitlist control groups. The intervention group received a 12-week home-based computerized EF intervention (5 days/week, 30 min/day, total dose 30 h). Core and higher-order EFs were assessed before, immediately after, and 9 months after completing the intervention. The intervention group performed better than the waitlist control group in the three core EFs (immediately and 9 months after the intervention): inhibitory control (F = 7.58, p = 0.13 and F = 7.85, p = 0.12), working memory (F = 8.34, p = 0.14 and F = 7.55, p = 0.13), and cognitive flexibility (F = 4.87, p = 0.09 and F = 4.19, p = 0.08). No differences were found between the groups in higher-order EFs or EF manifestations in daily life. Conclusions: A home-based computerized EF intervention improved core EFs in children with CP, but further research is needed to identify strategies that allow the transfer of these improvements to everyday life. Trial registration: NCT04025749 retrospectively registered on 19 July 2019. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00431-023-05072-3.
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spelling pubmed-105872732023-10-21 A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy García-Galant, María Blasco, Montse Laporta-Hoyos, Olga Berenguer-González, Alba Moral-Salicrú, Paula Ballester-Plané, Júlia Caldú, Xavier Miralbell, Júlia Alonso, Xènia Medina-Cantillo, Julita Povedano-Bulló, Elsa Leiva, David Boyd, Roslyn N. Pueyo, Roser Eur J Pediatr Research Children with cerebral palsy (CP) often show executive function (EF) impairments that are key to quality of life. The aim of this study was to assess whether a home-based computerized intervention program improves executive functions (EFs) compared to usual care. Sixty participants (30 females) with CP (8–12 years old) were paired by age, sex, motor ability, and intelligence quotient score and then randomized to intervention and waitlist control groups. The intervention group received a 12-week home-based computerized EF intervention (5 days/week, 30 min/day, total dose 30 h). Core and higher-order EFs were assessed before, immediately after, and 9 months after completing the intervention. The intervention group performed better than the waitlist control group in the three core EFs (immediately and 9 months after the intervention): inhibitory control (F = 7.58, p = 0.13 and F = 7.85, p = 0.12), working memory (F = 8.34, p = 0.14 and F = 7.55, p = 0.13), and cognitive flexibility (F = 4.87, p = 0.09 and F = 4.19, p = 0.08). No differences were found between the groups in higher-order EFs or EF manifestations in daily life. Conclusions: A home-based computerized EF intervention improved core EFs in children with CP, but further research is needed to identify strategies that allow the transfer of these improvements to everyday life. Trial registration: NCT04025749 retrospectively registered on 19 July 2019. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00431-023-05072-3. Springer Berlin Heidelberg 2023-07-18 2023 /pmc/articles/PMC10587273/ /pubmed/37462799 http://dx.doi.org/10.1007/s00431-023-05072-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
García-Galant, María
Blasco, Montse
Laporta-Hoyos, Olga
Berenguer-González, Alba
Moral-Salicrú, Paula
Ballester-Plané, Júlia
Caldú, Xavier
Miralbell, Júlia
Alonso, Xènia
Medina-Cantillo, Julita
Povedano-Bulló, Elsa
Leiva, David
Boyd, Roslyn N.
Pueyo, Roser
A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title_full A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title_fullStr A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title_full_unstemmed A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title_short A randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
title_sort randomized controlled trial of a home-based computerized executive function intervention for children with cerebral palsy
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587273/
https://www.ncbi.nlm.nih.gov/pubmed/37462799
http://dx.doi.org/10.1007/s00431-023-05072-3
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