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Histological spatial analysis on the induction of PD-L1(+) macrophages by CD8(+) T cells at the marginal microenvironment of triple-negative breast cancer

BACKGROUND: Programmed death-ligand 1 (PD-L1) plays important roles in the evasion of antitumor immunity. Because we observed the localization of PD-L1-positive (PD-L1(+)) cells in the marginal region of triple-negative breast cancer (TNBC) specimens, we hypothesized that the marginal microenvironme...

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Detalles Bibliográficos
Autores principales: Suzuki, Kazushi, Ohe, Rintaro, Kabasawa, Takanobu, Kitaoka, Takumi, Kawai, Masaaki, Motoi, Fuyuhiko, Futakuchi, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587303/
https://www.ncbi.nlm.nih.gov/pubmed/37792212
http://dx.doi.org/10.1007/s12282-023-01507-9