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Astragaloside IV derivative HHQ16 ameliorates infarction-induced hypertrophy and heart failure through degradation of lncRNA4012/9456

Reversing ventricular remodeling represents a promising treatment for the post-myocardial infarction (MI) heart failure (HF). Here, we report a novel small molecule HHQ16, an optimized derivative of astragaloside IV, which effectively reversed infarction-induced myocardial remodeling and improved ca...

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Detalles Bibliográficos
Autores principales:	Wan, Jingjing, Zhang, Zhen, Wu, Chennan, Tian, Saisai, Zang, Yibei, Jin, Ge, Sun, Qingyan, Wang, Pin, Luan, Xin, Yang, Yili, Zhan, Xuelin, Ye, Lingyu Linda, Duan, Dayue Darrel, Liu, Xia, Zhang, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587311/ https://www.ncbi.nlm.nih.gov/pubmed/37857609 http://dx.doi.org/10.1038/s41392-023-01660-9

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