High-dimensional deconstruction of pancreatic cancer identifies tumor microenvironmental and developmental stemness features that predict survival

Numerous cell states are known to comprise the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME). However, the developmental stemness and co-occurrence of these cell states remain poorly defined. Here, we performed single-cell RNA sequencing (scRNA-seq) on a cohort of treatment-na...

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Detalles Bibliográficos
Autores principales: Storrs, Erik P., Chati, Prathamesh, Usmani, Abul, Sloan, Ian, Krasnick, Bradley A., Babbra, Ramandeep, Harris, Peter K., Sachs, Chloe M., Qaium, Faridi, Chatterjee, Deyali, Wetzel, Chris, Goedegebuure, S. Peter, Hollander, Thomas, Anthony, Hephzibah, Ponce, Jennifer, Khaliq, Ateeq M., Badiyan, Shahed, Kim, Hyun, Denardo, David G., Lang, Gabriel D., Cosgrove, Natalie D., Kushnir, Vladimir M., Early, Dayna S., Masood, Ashiq, Lim, Kian-Huat, Hawkins, William G., Ding, Li, Fields, Ryan C., Das, Koushik K., Chaudhuri, Aadel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587349/
https://www.ncbi.nlm.nih.gov/pubmed/37857854
http://dx.doi.org/10.1038/s41698-023-00455-z

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