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Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit
OBJECTIVE: To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital. SETTING: ADI was implemented in a 21-patient bone marrow unit. PATIENTS: Patients were bone marrow recipients on this u...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587385/ https://www.ncbi.nlm.nih.gov/pubmed/36912338 http://dx.doi.org/10.1017/ice.2023.37 |
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author | Reagan, Kelly A. Chan, David M. Vanhoozer, Ginger Bearman, Gonzalo |
author_facet | Reagan, Kelly A. Chan, David M. Vanhoozer, Ginger Bearman, Gonzalo |
author_sort | Reagan, Kelly A. |
collection | PubMed |
description | OBJECTIVE: To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital. SETTING: ADI was implemented in a 21-patient bone marrow unit. PATIENTS: Patients were bone marrow recipients on this unit. INTERVENTIONS: We compared active ADI, in which patients who tested positive for colonization of C. difficile before their hospital stay were placed under extra contact precautions, with cases not under ADI. RESULTS: Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs. CONCLUSIONS: Institutions with active BMT units should consider implementing ADI. |
format | Online Article Text |
id | pubmed-10587385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-105873852023-10-21 Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit Reagan, Kelly A. Chan, David M. Vanhoozer, Ginger Bearman, Gonzalo Infect Control Hosp Epidemiol Original Article OBJECTIVE: To model the effects of active detection and isolation (ADI) regarding Clostridioides difficile infection (CDI) in the bone marrow transplant (BMT) unit of our hospital. SETTING: ADI was implemented in a 21-patient bone marrow unit. PATIENTS: Patients were bone marrow recipients on this unit. INTERVENTIONS: We compared active ADI, in which patients who tested positive for colonization of C. difficile before their hospital stay were placed under extra contact precautions, with cases not under ADI. RESULTS: Within the BMT unit, ADI reduced total cases of CDI by 24.5% per year and reduced hospital-acquired cases by ∼84%. The results from our simulations also suggest that ADI can save ∼$67,600 per year in healthcare costs. CONCLUSIONS: Institutions with active BMT units should consider implementing ADI. Cambridge University Press 2023-10 2023-03-13 /pmc/articles/PMC10587385/ /pubmed/36912338 http://dx.doi.org/10.1017/ice.2023.37 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited. |
spellingShingle | Original Article Reagan, Kelly A. Chan, David M. Vanhoozer, Ginger Bearman, Gonzalo Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title | Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title_full | Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title_fullStr | Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title_full_unstemmed | Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title_short | Estimating the effect of active detection and isolation on Clostridioides difficile infections in a bone marrow transplant unit |
title_sort | estimating the effect of active detection and isolation on clostridioides difficile infections in a bone marrow transplant unit |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587385/ https://www.ncbi.nlm.nih.gov/pubmed/36912338 http://dx.doi.org/10.1017/ice.2023.37 |
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