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Three-stage model of helical membrane protein folding: Role of membrane-water interface as the intermediate stage vestibule for TM helices during their in membrano assembly

Integral membrane proteins (MPs) are dominated by transmembrane α-helical (TMH) proteins playing critical roles in cellular signaling processes. These proteins display a wide range of sizes from one TMH domain to at least 26 TMH domains and diverse structural folds. A common feature of most of these...

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Detalles Bibliográficos
Autores principales: Kawamala, Bridget-K., Abrol, Ravinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587497/
https://www.ncbi.nlm.nih.gov/pubmed/35926384
http://dx.doi.org/10.1016/j.bbrc.2022.07.006