Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

The NFE2L2 (NRF2) oncogene and transcription factor drives a gene expression program that promotes cancer progression, metabolic reprogramming, immune evasion, and chemoradiation resistance. Patient stratification by NRF2 activity may guide treatment decisions to improve outcome. Here, we developed...

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Detalles Bibliográficos
Autores principales: Wamsley, Nathan T., Wilkerson, Emily M., Guan, Li, LaPak, Kyle M., Schrank, Travis P., Holmes, Brittany J., Sprung, Robert W., Gilmore, Petra Erdmann, Gerndt, Sophie P., Jackson, Ryan S., Paniello, Randal C., Pipkorn, Patrik, Puram, Sidharth V., Rich, Jason T., Townsend, Reid R., Zevallos, José P., Zolkind, Paul, Le, Quynh-Thu, Goldfarb, Dennis, Major, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587640/
https://www.ncbi.nlm.nih.gov/pubmed/37716475
http://dx.doi.org/10.1016/j.mcpro.2023.100647

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