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Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district

Immunocompromised district refers to the area of the skin with altered immune response predisposing secondary diseases to develop in an immunocompetent individual. This might be explained by the theory of T‐cell exhaustion which is characterized by the impairment of the effector function of antigen‐...

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Autores principales: Mathur, Mahesh, Thakur, Neha, Jaiswal, Sunil, Maharjan, Srijana, Paudel, Supriya, Shrestha, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587649/
https://www.ncbi.nlm.nih.gov/pubmed/37867546
http://dx.doi.org/10.1002/ccr3.8067
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author Mathur, Mahesh
Thakur, Neha
Jaiswal, Sunil
Maharjan, Srijana
Paudel, Supriya
Shrestha, Anjali
author_facet Mathur, Mahesh
Thakur, Neha
Jaiswal, Sunil
Maharjan, Srijana
Paudel, Supriya
Shrestha, Anjali
author_sort Mathur, Mahesh
collection PubMed
description Immunocompromised district refers to the area of the skin with altered immune response predisposing secondary diseases to develop in an immunocompetent individual. This might be explained by the theory of T‐cell exhaustion which is characterized by the impairment of the effector function of antigen‐specific T cells due to chronic persistence of the primary antigen. T‐cell exhaustion model is not well known; however, it serves as a newer concept in the pathogenesis of diseases occurring simultaneously over the same site. Thus, it is not surprising to have two different infectious or non‐infectious dermatoses over the same site one preceding the other as observed in our patient. The concept of immunocompromised district and T‐cell exhaustion is a rare phenomenon; however, it should be identified by the treating physicians/dermatologists for the optimum management of the atypical presentation of the diseases.
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spelling pubmed-105876492023-10-21 Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district Mathur, Mahesh Thakur, Neha Jaiswal, Sunil Maharjan, Srijana Paudel, Supriya Shrestha, Anjali Clin Case Rep Case Report Immunocompromised district refers to the area of the skin with altered immune response predisposing secondary diseases to develop in an immunocompetent individual. This might be explained by the theory of T‐cell exhaustion which is characterized by the impairment of the effector function of antigen‐specific T cells due to chronic persistence of the primary antigen. T‐cell exhaustion model is not well known; however, it serves as a newer concept in the pathogenesis of diseases occurring simultaneously over the same site. Thus, it is not surprising to have two different infectious or non‐infectious dermatoses over the same site one preceding the other as observed in our patient. The concept of immunocompromised district and T‐cell exhaustion is a rare phenomenon; however, it should be identified by the treating physicians/dermatologists for the optimum management of the atypical presentation of the diseases. John Wiley and Sons Inc. 2023-10-19 /pmc/articles/PMC10587649/ /pubmed/37867546 http://dx.doi.org/10.1002/ccr3.8067 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Mathur, Mahesh
Thakur, Neha
Jaiswal, Sunil
Maharjan, Srijana
Paudel, Supriya
Shrestha, Anjali
Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title_full Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title_fullStr Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title_full_unstemmed Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title_short Herpes zoster occurring over the site of tinea cruris—A case report based on the model of T‐cell exhaustion in the Ruocco's immunocompromised cutaneous district
title_sort herpes zoster occurring over the site of tinea cruris—a case report based on the model of t‐cell exhaustion in the ruocco's immunocompromised cutaneous district
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587649/
https://www.ncbi.nlm.nih.gov/pubmed/37867546
http://dx.doi.org/10.1002/ccr3.8067
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