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Correlations among the plasma concentrations of first-line anti-tuberculosis drugs and the physiological parameters influencing concentrations

Background: The plasma concentrations of the four most commonly used first-line anti-tuberculosis (TB) drugs, isoniazid (INH), rifampicin (RMP), ethambutol (EMB), and pyrazinamide (PZA), are often not within the therapeutic range. Insufficient drug exposure could lead to drug resistance and treatmen...

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Detalles Bibliográficos
Autores principales: Cheng, Lin, Luo, Ming, Guo, Yan, Fan, Yunfan, Wang, Pengsen, Zhou, Gang, Qin, Shiwei, Weng, Bangbi, Li, Peibo, Liu, Zhirui, Liu, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587680/
https://www.ncbi.nlm.nih.gov/pubmed/37869746
http://dx.doi.org/10.3389/fphar.2023.1248331