Pyrrolizine/indolizine-bearing (un)substituted isoindole moiety: design, synthesis, antiproliferative and MDR reversal activities, and in silico studies

Two new series of pyrrolizine/indolizine derivative-bearing (un)substituted isoindole moiety were designed and synthesized. The anticancer potential of the new compounds was evaluated against hepatocellular carcinoma (HepG-2), colorectal carcinoma, colon cancer (HCT-116), and breast cancer (MCF-7) c...

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Detalles Bibliográficos
Autores principales: AbdelSamad, Amr L., El-Saadi, Mohammed T., Gouda, Ahmed M., AboulMagd, Asmaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587743/
https://www.ncbi.nlm.nih.gov/pubmed/37869384
http://dx.doi.org/10.1039/d3ra05310e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587743/
https://www.ncbi.nlm.nih.gov/pubmed/37869384
http://dx.doi.org/10.1039/d3ra05310e

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