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Integration of bioinformatics and machine learning strategies identifies APM-related gene signatures to predict clinical outcomes and therapeutic responses for breast cancer patients

BACKGROUND: Tumor antigenicity and efficiency of antigen presentation jointly influence tumor immunogenicity, which largely determines the effectiveness of immune checkpoint blockade (ICB). However, the role of altered antigen processing and presentation machinery (APM) in breast cancer (BRCA) has n...

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Detalles Bibliográficos
Autores principales: Shen, Hong-yu, Xu, Jia-lin, Zhu, Zhen, Xu, Hai-ping, Liang, Ming-xing, Xu, Di, Chen, Wen-quan, Tang, Jin-hai, Fang, Zheng, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587768/
https://www.ncbi.nlm.nih.gov/pubmed/37839160
http://dx.doi.org/10.1016/j.neo.2023.100942

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