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YTHDF1 mitigates acute kidney injury via safeguarding m(6)A-methylated mRNAs in stress granules of renal tubules

Acute kidney injury (AKI) presents a daunting challenge with limited therapeutic options. To explore the contribution of N(6)-methyladenosine (m(6)A) in AKI development, we have investigated m(6)A-modified mRNAs within renal tubular cells subjected to injuries induced by diverse stressors. Notably,...

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Detalles Bibliográficos
Autores principales: Yang, Wenwen, Zhang, Mingchao, Li, Jiacheng, Qu, Shuang, Zhou, Fenglian, Liu, Minghui, Li, Limin, Liu, Zhihong, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587769/
https://www.ncbi.nlm.nih.gov/pubmed/37857002
http://dx.doi.org/10.1016/j.redox.2023.102921