IL-8 Triggers Neutrophil Extracellular Trap Formation Through an Nicotinamide Adenine Dinucleotide Phosphate Oxidase- and Mitogen-Activated Protein Kinase Pathway-Dependent Mechanism in Uveitis

PURPOSE: To explore the mechanism underlying IL-8-induced neutrophil extracellular trap (NET) formation in patients with ocular-active Behçet's disease (BD) and the effect of inhibiting NET formation on the severity of inflammation in experimental autoimmune uveitis (EAU) mice. METHODS: The ser...

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Detalles Bibliográficos
Autores principales: Shu, Qinxin, Zhang, Ni, Liu, Yanyao, Wang, Xing, Chen, Jinquan, Xie, Hao, Pan, Fuying, Zhao, Long, Ding, Xuanheng, Wen, Yan, Wang, Lingda, Xie, Wenxi, Lu, Jing, Su, Guannan, Peng, Hui, Yang, Peizeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587853/
https://www.ncbi.nlm.nih.gov/pubmed/37824136
http://dx.doi.org/10.1167/iovs.64.13.19

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