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Self-Adjuvanting TLR7/8 Agonist and Fentanyl Hapten Co-Conjugate Achieves Enhanced Protection against Fentanyl Challenge
[Image: see text] Currently approved pharmacotherapies for opioid use disorders (OUDs) and overdose reversal agents are insufficient to slow the spread of OUDs due to the proliferation of fentanyl. This is evident in the 31% rise in drug overdose deaths from 2019 to 2022, with rates increasing from...
Autores principales: | Powers, Noah, Massena, Casey, Crouse, Bethany, Smith, Mira, Hicks, Linda, Evans, Jay T., Miller, Shannon, Pravetoni, Marco, Burkhart, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587865/ https://www.ncbi.nlm.nih.gov/pubmed/37758302 http://dx.doi.org/10.1021/acs.bioconjchem.3c00347 |
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