Cargando…
Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis
BACKGROUND: China has a high mortality from nasopharyngeal carcinoma (NPC). The NPC mortality trends in China from 2006 to 2020 were described and analyzed to understand its epidemiological characteristics by region and sex and to explore age, period, and cohort effects. METHODS: This study utilized...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588046/ https://www.ncbi.nlm.nih.gov/pubmed/37864181 http://dx.doi.org/10.1186/s12889-023-16892-1 |
_version_ | 1785123494483197952 |
---|---|
author | Guo, Xinru Cui, Jiameng Yuan, Xin Gao, Zibo Yu, Ge Wu, Hao Kou, Changgui |
author_facet | Guo, Xinru Cui, Jiameng Yuan, Xin Gao, Zibo Yu, Ge Wu, Hao Kou, Changgui |
author_sort | Guo, Xinru |
collection | PubMed |
description | BACKGROUND: China has a high mortality from nasopharyngeal carcinoma (NPC). The NPC mortality trends in China from 2006 to 2020 were described and analyzed to understand its epidemiological characteristics by region and sex and to explore age, period, and cohort effects. METHODS: This study utilized NPC mortality data from the China Health Statistical Yearbook. A joinpoint regression model was used to fit the standardized NPC mortality and age-specific mortality. The age-period-cohort model was applied to investigate age, period, and cohort effects on NPC mortality risk. RESULTS: The results showed that the NPC mortality rate in China has been declining steadily. From 2006 to 2020, the standardized NPC mortality rate in most age groups showed a significant downward trend. The annual percentage change was smaller in rural areas than in urban areas. The mortality risks of rural males and rural females from 2016 to 2020 were 1.139 times and 1.080 times those from 2011 to 2015, respectively. Both urban males born in 1984–1988 and rural males born in 1979–1983 exhibited an increasing trend in NPC mortality risk. CONCLUSIONS: Our study confirmed the effectiveness of NPC prevention and treatment strategies in China from 2006 to 2020. However, it underscored the urgent need for targeted interventions in rural areas to further reduce NPC mortality rates. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-16892-1. |
format | Online Article Text |
id | pubmed-10588046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-105880462023-10-21 Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis Guo, Xinru Cui, Jiameng Yuan, Xin Gao, Zibo Yu, Ge Wu, Hao Kou, Changgui BMC Public Health Research BACKGROUND: China has a high mortality from nasopharyngeal carcinoma (NPC). The NPC mortality trends in China from 2006 to 2020 were described and analyzed to understand its epidemiological characteristics by region and sex and to explore age, period, and cohort effects. METHODS: This study utilized NPC mortality data from the China Health Statistical Yearbook. A joinpoint regression model was used to fit the standardized NPC mortality and age-specific mortality. The age-period-cohort model was applied to investigate age, period, and cohort effects on NPC mortality risk. RESULTS: The results showed that the NPC mortality rate in China has been declining steadily. From 2006 to 2020, the standardized NPC mortality rate in most age groups showed a significant downward trend. The annual percentage change was smaller in rural areas than in urban areas. The mortality risks of rural males and rural females from 2016 to 2020 were 1.139 times and 1.080 times those from 2011 to 2015, respectively. Both urban males born in 1984–1988 and rural males born in 1979–1983 exhibited an increasing trend in NPC mortality risk. CONCLUSIONS: Our study confirmed the effectiveness of NPC prevention and treatment strategies in China from 2006 to 2020. However, it underscored the urgent need for targeted interventions in rural areas to further reduce NPC mortality rates. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-023-16892-1. BioMed Central 2023-10-20 /pmc/articles/PMC10588046/ /pubmed/37864181 http://dx.doi.org/10.1186/s12889-023-16892-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Guo, Xinru Cui, Jiameng Yuan, Xin Gao, Zibo Yu, Ge Wu, Hao Kou, Changgui Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title | Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title_full | Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title_fullStr | Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title_full_unstemmed | Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title_short | Long-term trends of nasopharyngeal carcinoma mortality in China from 2006 to 2020 by region and sex: an age-period-cohort analysis |
title_sort | long-term trends of nasopharyngeal carcinoma mortality in china from 2006 to 2020 by region and sex: an age-period-cohort analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588046/ https://www.ncbi.nlm.nih.gov/pubmed/37864181 http://dx.doi.org/10.1186/s12889-023-16892-1 |
work_keys_str_mv | AT guoxinru longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT cuijiameng longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT yuanxin longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT gaozibo longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT yuge longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT wuhao longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis AT kouchanggui longtermtrendsofnasopharyngealcarcinomamortalityinchinafrom2006to2020byregionandsexanageperiodcohortanalysis |