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GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership
Parts-based representations, such as non-negative matrix factorization and topic modeling, have been used to identify structure from single-cell sequencing data sets, in particular structure that is not as well captured by clustering or other dimensionality reduction methods. However, interpreting t...
Autores principales: | Carbonetto, Peter, Luo, Kaixuan, Sarkar, Abhishek, Hung, Anthony, Tayeb, Karl, Pott, Sebastian, Stephens, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588049/ https://www.ncbi.nlm.nih.gov/pubmed/37858253 http://dx.doi.org/10.1186/s13059-023-03067-9 |
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