Cargando…
Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice
INTRODUCTION: Glucose transporter 1 (GLUT1) is essential for glucose transport into the brain and is predominantly expressed in the cerebral microvasculature. Downregulation of GLUT1 precedes the development of cognitive impairment in neurodegenerative conditions. Surgical trauma induces blood–brain...
Autores principales: | Chen, Ying, Joo, Jin, Chu, John Man-Tak, Chang, Raymond Chuen-Chung, Wong, Gordon Tin-Chun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588063/ https://www.ncbi.nlm.nih.gov/pubmed/37858199 http://dx.doi.org/10.1186/s12974-023-02905-8 |
Ejemplares similares
-
Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein
por: Tang, Maoxue, et al.
Publicado: (2017) -
Prehabilitative resistance exercise reduces neuroinflammation and improves mitochondrial health in aged mice with perioperative neurocognitive disorders
por: Liu, Yan, et al.
Publicado: (2022) -
Development of Glucose Transporter (GLUT) Inhibitors
por: Reckzeh, Elena S., et al.
Publicado: (2019) -
Expression of the glucose transporters GLUT1, GLUT3, GLUT4 and GLUT12 in human cancer cells
por: Barron, Carly, et al.
Publicado: (2012) -
Modelling the effects of cerebral microvasculature morphology on oxygen transport
por: Park, Chang Sub, et al.
Publicado: (2016)