IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

BACKGROUND: Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/ARDS. Thus, ameliorating inflammatory reacti...

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Detalles Bibliográficos
Autores principales: Yan, Chunguang, Chen, Jing, Tang, Huifang, Deng, Chunmin, Zhang, Qi, Wang, Ximo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588139/
https://www.ncbi.nlm.nih.gov/pubmed/37864223
http://dx.doi.org/10.1186/s12950-023-00359-6

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