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Impairing Gasdermin D-mediated pyroptosis is protective against retinal degeneration

BACKGROUND: Inflammasome activation and the subsequent release of pro-inflammatory cytokines including Interleukin 1β (IL-1β) have been widely reported to contribute to the progression of retinal degenerations, including age-related macular degeneration (AMD), the leading cause of blindness in the W...

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Detalles Bibliográficos
Autores principales:	Sekar, Rakshanya, Wooff, Yvette, Cioanca, Adrian V., Kurera, Melan, Ngo, Chinh, Man, Si Ming, Natoli, Riccardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588253/ https://www.ncbi.nlm.nih.gov/pubmed/37864169 http://dx.doi.org/10.1186/s12974-023-02927-2

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