Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits

Understanding differences in adipose gene expression between individuals with different levels of clinical traits may reveal the genes and mechanisms leading to cardiometabolic diseases. However, adipose is a heterogeneous tissue. To account for cell-type heterogeneity, we estimated cell-type propor...

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Detalles Bibliográficos
Autores principales: Brotman, Sarah M., Oravilahti, Anniina, Rosen, Jonathan D., Alvarez, Marcus, Heinonen, Sini, van der Kolk, Birgitta W., Fernandes Silva, Lilian, Perrin, Hannah J., Vadlamudi, Swarooparani, Pylant, Cortney, Deochand, Sonia, Basta, Patricia V., Valone, Jordan M., Narain, Morgan N., Stringham, Heather M., Boehnke, Michael, Kuusisto, Johanna, Love, Michael I., Pietiläinen, Kirsi H., Pajukanta, Päivi, Laakso, Markku, Mohlke, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588284/
https://www.ncbi.nlm.nih.gov/pubmed/37647564
http://dx.doi.org/10.2337/db23-0365

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