Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023

New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (Kp) ST147 caused a large multi-hospital outbreak in Italy from 2018 to 2021. We describe a new ST6668 NDM-producing Kp clone, belonging to CC147, which rapidly spread across hospitals in the Pavia province (Northern Italy) from...

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Autores principales: Mileto, Irene, Petazzoni, Greta, Corbella, Marta, Gaiarsa, Stefano, Merla, Cristina, Kuka, Angela, Ramus, Marina, Terulla, Cristina, Brandolini, Micaela, Piralla, Antonio, Cambieri, Patrizia, Baldanti, Fausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2023
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588309/
https://www.ncbi.nlm.nih.gov/pubmed/37855902
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.42.2300522
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author Mileto, Irene
Petazzoni, Greta
Corbella, Marta
Gaiarsa, Stefano
Merla, Cristina
Kuka, Angela
Ramus, Marina
Terulla, Cristina
Brandolini, Micaela
Piralla, Antonio
Cambieri, Patrizia
Baldanti, Fausto
author_facet Mileto, Irene
Petazzoni, Greta
Corbella, Marta
Gaiarsa, Stefano
Merla, Cristina
Kuka, Angela
Ramus, Marina
Terulla, Cristina
Brandolini, Micaela
Piralla, Antonio
Cambieri, Patrizia
Baldanti, Fausto
author_sort Mileto, Irene
collection PubMed
description New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (Kp) ST147 caused a large multi-hospital outbreak in Italy from 2018 to 2021. We describe a new ST6668 NDM-producing Kp clone, belonging to CC147, which rapidly spread across hospitals in the Pavia province (Northern Italy) from February to August 2023. Genomic analyses revealed that ST6668 is different from ST147 and fast evolving. As shown here, genomic surveillance programmes are useful for tracking the spread of new clones with reduced susceptibility to most antibiotics.
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spelling pubmed-105883092023-10-21 Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023 Mileto, Irene Petazzoni, Greta Corbella, Marta Gaiarsa, Stefano Merla, Cristina Kuka, Angela Ramus, Marina Terulla, Cristina Brandolini, Micaela Piralla, Antonio Cambieri, Patrizia Baldanti, Fausto Euro Surveill Rapid Communication New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (Kp) ST147 caused a large multi-hospital outbreak in Italy from 2018 to 2021. We describe a new ST6668 NDM-producing Kp clone, belonging to CC147, which rapidly spread across hospitals in the Pavia province (Northern Italy) from February to August 2023. Genomic analyses revealed that ST6668 is different from ST147 and fast evolving. As shown here, genomic surveillance programmes are useful for tracking the spread of new clones with reduced susceptibility to most antibiotics. European Centre for Disease Prevention and Control (ECDC) 2023-10-19 /pmc/articles/PMC10588309/ /pubmed/37855902 http://dx.doi.org/10.2807/1560-7917.ES.2023.28.42.2300522 Text en This article is copyright of the authors or their affiliated institutions, 2023. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Mileto, Irene
Petazzoni, Greta
Corbella, Marta
Gaiarsa, Stefano
Merla, Cristina
Kuka, Angela
Ramus, Marina
Terulla, Cristina
Brandolini, Micaela
Piralla, Antonio
Cambieri, Patrizia
Baldanti, Fausto
Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title_full Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title_fullStr Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title_full_unstemmed Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title_short Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
title_sort rapid spread of a novel ndm-producing clone of klebsiella pneumoniae cc147, northern italy, february to august 2023
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588309/
https://www.ncbi.nlm.nih.gov/pubmed/37855902
http://dx.doi.org/10.2807/1560-7917.ES.2023.28.42.2300522
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