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Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn pa...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588345/ https://www.ncbi.nlm.nih.gov/pubmed/37245866 http://dx.doi.org/10.1111/iwj.14243 |
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author | Li, Rui Zheng, Yangyang Fan, Xijuan Cao, Zilong Yue, Qiang Fan, Jincai Gan, Cheng Jiao, Hu Liu, Liqiang |
author_facet | Li, Rui Zheng, Yangyang Fan, Xijuan Cao, Zilong Yue, Qiang Fan, Jincai Gan, Cheng Jiao, Hu Liu, Liqiang |
author_sort | Li, Rui |
collection | PubMed |
description | Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn patients and to develop a nomogram to predict the risk of neck contracture after skin grafting in burn patients. Data from 212 patients with burns who underwent neck skin grafting were collected from three hospitals, and the patients were randomly divided into training and validation sets. Independent predictors were identified through univariate and multivariate logistic regression analyses and incorporated into a prognostic nomogram. Its performance was assessed using the receiver operating characteristic area under the curve, calibration curve, and decision curve analysis. Burn depth, combined cervicothoracic skin grafting, graft thickness, and neck graft size were significantly associated with neck contractures. In the training cohort, the nomogram had an area under the curve of 0.894. The calibration curve and decision curve analysis indicated good clinical applicability of the nomogram. The results were tested using a validation dataset. Combined cervicothoracic skin grafting is an independent risk factor for neck contracture. Our nomogram demonstrated excellent performance in predicting neck contracture risk. |
format | Online Article Text |
id | pubmed-10588345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-105883452023-10-21 Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study Li, Rui Zheng, Yangyang Fan, Xijuan Cao, Zilong Yue, Qiang Fan, Jincai Gan, Cheng Jiao, Hu Liu, Liqiang Int Wound J Original Articles Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn patients and to develop a nomogram to predict the risk of neck contracture after skin grafting in burn patients. Data from 212 patients with burns who underwent neck skin grafting were collected from three hospitals, and the patients were randomly divided into training and validation sets. Independent predictors were identified through univariate and multivariate logistic regression analyses and incorporated into a prognostic nomogram. Its performance was assessed using the receiver operating characteristic area under the curve, calibration curve, and decision curve analysis. Burn depth, combined cervicothoracic skin grafting, graft thickness, and neck graft size were significantly associated with neck contractures. In the training cohort, the nomogram had an area under the curve of 0.894. The calibration curve and decision curve analysis indicated good clinical applicability of the nomogram. The results were tested using a validation dataset. Combined cervicothoracic skin grafting is an independent risk factor for neck contracture. Our nomogram demonstrated excellent performance in predicting neck contracture risk. Blackwell Publishing Ltd 2023-05-28 /pmc/articles/PMC10588345/ /pubmed/37245866 http://dx.doi.org/10.1111/iwj.14243 Text en © 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Li, Rui Zheng, Yangyang Fan, Xijuan Cao, Zilong Yue, Qiang Fan, Jincai Gan, Cheng Jiao, Hu Liu, Liqiang Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title | Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title_full | Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title_fullStr | Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title_full_unstemmed | Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title_short | Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study |
title_sort | establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: a multicentre cohort study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588345/ https://www.ncbi.nlm.nih.gov/pubmed/37245866 http://dx.doi.org/10.1111/iwj.14243 |
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