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Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study

Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn pa...

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Autores principales: Li, Rui, Zheng, Yangyang, Fan, Xijuan, Cao, Zilong, Yue, Qiang, Fan, Jincai, Gan, Cheng, Jiao, Hu, Liu, Liqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588345/
https://www.ncbi.nlm.nih.gov/pubmed/37245866
http://dx.doi.org/10.1111/iwj.14243
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author Li, Rui
Zheng, Yangyang
Fan, Xijuan
Cao, Zilong
Yue, Qiang
Fan, Jincai
Gan, Cheng
Jiao, Hu
Liu, Liqiang
author_facet Li, Rui
Zheng, Yangyang
Fan, Xijuan
Cao, Zilong
Yue, Qiang
Fan, Jincai
Gan, Cheng
Jiao, Hu
Liu, Liqiang
author_sort Li, Rui
collection PubMed
description Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn patients and to develop a nomogram to predict the risk of neck contracture after skin grafting in burn patients. Data from 212 patients with burns who underwent neck skin grafting were collected from three hospitals, and the patients were randomly divided into training and validation sets. Independent predictors were identified through univariate and multivariate logistic regression analyses and incorporated into a prognostic nomogram. Its performance was assessed using the receiver operating characteristic area under the curve, calibration curve, and decision curve analysis. Burn depth, combined cervicothoracic skin grafting, graft thickness, and neck graft size were significantly associated with neck contractures. In the training cohort, the nomogram had an area under the curve of 0.894. The calibration curve and decision curve analysis indicated good clinical applicability of the nomogram. The results were tested using a validation dataset. Combined cervicothoracic skin grafting is an independent risk factor for neck contracture. Our nomogram demonstrated excellent performance in predicting neck contracture risk.
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spelling pubmed-105883452023-10-21 Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study Li, Rui Zheng, Yangyang Fan, Xijuan Cao, Zilong Yue, Qiang Fan, Jincai Gan, Cheng Jiao, Hu Liu, Liqiang Int Wound J Original Articles Cervical burn contracture is one of the burn contractures with the highest incidence and severity, and there is no effective method to predict the risk of neck contracture. This study aimed to investigate the effect of combined cervicothoracic skin grafting on the risk of neck contracture in burn patients and to develop a nomogram to predict the risk of neck contracture after skin grafting in burn patients. Data from 212 patients with burns who underwent neck skin grafting were collected from three hospitals, and the patients were randomly divided into training and validation sets. Independent predictors were identified through univariate and multivariate logistic regression analyses and incorporated into a prognostic nomogram. Its performance was assessed using the receiver operating characteristic area under the curve, calibration curve, and decision curve analysis. Burn depth, combined cervicothoracic skin grafting, graft thickness, and neck graft size were significantly associated with neck contractures. In the training cohort, the nomogram had an area under the curve of 0.894. The calibration curve and decision curve analysis indicated good clinical applicability of the nomogram. The results were tested using a validation dataset. Combined cervicothoracic skin grafting is an independent risk factor for neck contracture. Our nomogram demonstrated excellent performance in predicting neck contracture risk. Blackwell Publishing Ltd 2023-05-28 /pmc/articles/PMC10588345/ /pubmed/37245866 http://dx.doi.org/10.1111/iwj.14243 Text en © 2023 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Li, Rui
Zheng, Yangyang
Fan, Xijuan
Cao, Zilong
Yue, Qiang
Fan, Jincai
Gan, Cheng
Jiao, Hu
Liu, Liqiang
Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title_full Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title_fullStr Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title_full_unstemmed Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title_short Establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: A multicentre cohort study
title_sort establishment and validation of a nomogram to predict the neck contracture after skin grafting in burn patients: a multicentre cohort study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588345/
https://www.ncbi.nlm.nih.gov/pubmed/37245866
http://dx.doi.org/10.1111/iwj.14243
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