Metabolic regulation of forkhead box P3 alternative splicing isoforms and their impact on health and disease

Forkhead Box P3 (FOXP3) is crucial for the development and suppressive function of human regulatory T cells (Tregs). There are two predominant FOXP3 splicing isoforms in healthy humans, the full-length isoform and the isoform lacking exon 2, with different functions and regulation mechanisms. FOXP3...

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Detalles Bibliográficos
Autores principales: Luo, Zhidan, Zhang, Yihua, Saleh, Qais Waleed, Zhang, Jie, Zhu, Zhiming, Tepel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588449/
https://www.ncbi.nlm.nih.gov/pubmed/37868998
http://dx.doi.org/10.3389/fimmu.2023.1278560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588449/
https://www.ncbi.nlm.nih.gov/pubmed/37868998
http://dx.doi.org/10.3389/fimmu.2023.1278560

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