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Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes

YidC belongs to an evolutionarily conserved family of insertases, YidC/Oxa1/Alb3, in bacteria, mitochondria, and chloroplasts, respectively. Unlike Gram-negative bacteria, Gram-positives including Streptococcus mutans harbor two paralogs of YidC. The mechanism for paralog-specific phenotypes of bact...

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Detalles Bibliográficos
Autores principales: Mishra, Surabhi, van Aalst, Evan J., Wylie, Benjamin J., Brady, L. Jeannine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588454/
https://www.ncbi.nlm.nih.gov/pubmed/37867558
http://dx.doi.org/10.3389/fmolb.2023.1264454

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