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A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display

Despite being one of the commonest malignancies among women worldwide, carcinoma of the cervix, due to its nonspecific symptoms, goes undiagnosed until it reaches advanced stages. This is especially true among women living with human immunodeficiency virus (HIV) as the rate of screening for them is...

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Autores principales: Pamnani, Soumya, Bakshi, Sanket S, Chakole, Swarupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588535/
https://www.ncbi.nlm.nih.gov/pubmed/37868493
http://dx.doi.org/10.7759/cureus.45605
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author Pamnani, Soumya
Bakshi, Sanket S
Chakole, Swarupa
author_facet Pamnani, Soumya
Bakshi, Sanket S
Chakole, Swarupa
author_sort Pamnani, Soumya
collection PubMed
description Despite being one of the commonest malignancies among women worldwide, carcinoma of the cervix, due to its nonspecific symptoms, goes undiagnosed until it reaches advanced stages. This is especially true among women living with human immunodeficiency virus (HIV) as the rate of screening for them is much less as compared to noninfected women. HIV infection greatly impacts the treatment and the prognosis of the diagnosed carcinoma. The existing common linkage between the occurrence of HIV and that of cervical cancer has some significant common elements such as low socio-economic conditions and poor hygiene. The treatment methods in such cases, prove to be of concern, taking into consideration the seropositive status of the case. Here, we discuss one such case of a seropositive patient who presented with complaints of leukorrhea, dysmenorrhea, and dyspareunia. She had stable vitals, with a pulse rate of 86/minute and blood pressure of 100/80 mmHg. On clinical examination, she was diagnosed with stage International Federation of Gynecology and Obstetrics (FIGO) IIIB cervical carcinoma. Under all aseptic precautions, a cervical biopsy was taken and moderately differentiated squamous cell carcinoma of the cervix was diagnosed. A multidisciplinary approach was decided as the course of action, after which she was referred to the department of medical oncology for chemoradiation. Five cycles with a dose of ten Gray (GY) per cycle were planned with concurrent chemotherapy with cisplatin per week. The patient was advised to follow up in the gynecology outpatient department after completion of her chemoradiation cycles for further evaluation and management. 
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spelling pubmed-105885352023-10-21 A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display Pamnani, Soumya Bakshi, Sanket S Chakole, Swarupa Cureus Obstetrics/Gynecology Despite being one of the commonest malignancies among women worldwide, carcinoma of the cervix, due to its nonspecific symptoms, goes undiagnosed until it reaches advanced stages. This is especially true among women living with human immunodeficiency virus (HIV) as the rate of screening for them is much less as compared to noninfected women. HIV infection greatly impacts the treatment and the prognosis of the diagnosed carcinoma. The existing common linkage between the occurrence of HIV and that of cervical cancer has some significant common elements such as low socio-economic conditions and poor hygiene. The treatment methods in such cases, prove to be of concern, taking into consideration the seropositive status of the case. Here, we discuss one such case of a seropositive patient who presented with complaints of leukorrhea, dysmenorrhea, and dyspareunia. She had stable vitals, with a pulse rate of 86/minute and blood pressure of 100/80 mmHg. On clinical examination, she was diagnosed with stage International Federation of Gynecology and Obstetrics (FIGO) IIIB cervical carcinoma. Under all aseptic precautions, a cervical biopsy was taken and moderately differentiated squamous cell carcinoma of the cervix was diagnosed. A multidisciplinary approach was decided as the course of action, after which she was referred to the department of medical oncology for chemoradiation. Five cycles with a dose of ten Gray (GY) per cycle were planned with concurrent chemotherapy with cisplatin per week. The patient was advised to follow up in the gynecology outpatient department after completion of her chemoradiation cycles for further evaluation and management.  Cureus 2023-09-20 /pmc/articles/PMC10588535/ /pubmed/37868493 http://dx.doi.org/10.7759/cureus.45605 Text en Copyright © 2023, Pamnani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Pamnani, Soumya
Bakshi, Sanket S
Chakole, Swarupa
A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title_full A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title_fullStr A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title_full_unstemmed A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title_short A Dire Presentation of Carcinoma Cervix in a Human Immunodeficiency Virus-Positive Case: A Salient Display
title_sort dire presentation of carcinoma cervix in a human immunodeficiency virus-positive case: a salient display
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588535/
https://www.ncbi.nlm.nih.gov/pubmed/37868493
http://dx.doi.org/10.7759/cureus.45605
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