Cargando…

MiR-21 Participates in Anti-VEGF-Induced Epithelial Mesenchymal Transformation in RPE Cells

BACKGROUND: To explore the role and possible mechanism of miR-21 in anti-VEGF drug-induced epithelial-mesenchymal transformation (EMT) in human retinal pigment epithelium (ARPE-19) cells, and to seek more therapeutic targets to improve prognosis vision. METHODS: ARPE-19 cells were exposed to clinica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Xianghui, Hua, Yingbin, Xie, Chaohui, Xu, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588660/ https://www.ncbi.nlm.nih.gov/pubmed/37869043 http://dx.doi.org/10.2147/OPTH.S427894

Ejemplares similares

Basal and apical regulation of VEGF-A and placenta growth factor in the RPE/choroid and primary RPE
por: Klettner, Alexa, et al.
Publicado: (2015)

MiR-21 Is Required for the Epithelial–Mesenchymal Transition in MDA-MB-231 Breast Cancer Cells
por: Arisan, Elif Damla, et al.
Publicado: (2021)

The Influence of Melatonin and Light on VEGF Secretion in Primary RPE Cells
por: Klettner, Alexa, et al.
Publicado: (2021)

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell–Derived RPE
por: Sripathi, Srinivasa R., et al.
Publicado: (2021)

miR-877-5p Inhibits Epithelial Mesenchymal Transformation of Breast Cancer Cells by Targeting FGB
por: Liu, Haixia, et al.
Publicado: (2022)

miR-186 regulates epithelial–mesenchymal transformation to promote nasopharyngeal carcinoma metastasis by targeting ZEB1()
por: Tang, Liangke, et al.
Publicado: (2023)

HPV-Induced MiR-21 Promotes Epithelial Mesenchymal Transformation and Tumor Progression in Cervical Cancer Cells through the TGFβ R2/hTERC Pathway
por: Han, Ying, et al.
Publicado: (2022)

Simultaneous downregulation of miR-21 and upregulation of miR-7 has anti-tumor efficacy
por: Bhere, Deepak, et al.
Publicado: (2020)

MEG3/miR-21 axis affects cell mobility by suppressing epithelial-mesenchymal transition in gastric cancer
por: Xu, Gang, et al.
Publicado: (2018)

Upregulated Wnt-11 and miR-21 Expression Trigger Epithelial Mesenchymal Transition in Aggressive Prostate Cancer Cells
por: Arisan, Elif Damla, et al.
Publicado: (2020)

MiR-21-5p in Macrophage-Derived Exosomes Targets Smad7 to Promote Epithelial Mesenchymal Transition of Airway Epithelial Cells
por: Li, Xiang, et al.
Publicado: (2021)

RPE epithelial-mesenchymal transition plays a critical role in the pathogenesis of proliferative vitreoretinopathy
por: Li, Xiaohua, et al.
Publicado: (2020)

Interactive role of miR‐29, miR‐93, miR‐205, and VEGF in salivary adenoid cystic carcinoma
por: Bayat, Parisa, et al.
Publicado: (2022)

miR-21 and KLF4 jointly augment epithelial-mesenchymal transition via the Akt/ERK1/2 pathway
por: Liu, Chen-Hai, et al.
Publicado: (2017)

Downregulated lncRNA GAS5 and Upregulated miR-21 Lead to Epithelial–Mesenchymal Transition and Lung Metastasis of Osteosarcomas
por: Wang, Ying, et al.
Publicado: (2021)

JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells
por: Liu, Li-Hua, et al.
Publicado: (2022)

Cell fusion between gastric epithelial cells and mesenchymal stem cells results in epithelial-to-mesenchymal transition and malignant transformation
por: He, Xianghui, et al.
Publicado: (2015)

Suspension of Anti-VEGF Treatment Does Not Affect Expansion of RPE Atrophy in Neovascular Age-Related Macular Degeneration
por: Chujo, Shinichiro, et al.
Publicado: (2023)

MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
por: Xue, Xiaofeng, et al.
Publicado: (2014)

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma
por: Liu, Tianrun, et al.
Publicado: (2018)

miR-122 inhibits metastasis and epithelial–mesenchymal transition of non-small-cell lung cancer cells
por: Qin, Haifeng, et al.
Publicado: (2015)

Physical disruption of cell–cell contact induces VEGF expression in RPE cells
por: Farjood, Farhad, et al.
Publicado: (2017)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

miR-21 Promotes Keratinocyte Migration and Re-epithelialization During Wound Healing
por: Yang, Xue, et al.
Publicado: (2011)

miR-21 Promotes Keratinocyte Migration and Re-epithelialization during Wound Healing
por: Yang, Xue, et al.
Publicado: (2013)

Complete RPE and outer retinal atrophy in patients receiving anti-VEGF treatment for neovascular age-related macular degeneration
por: Eng, Victor A., et al.
Publicado: (2020)

MiR-302d inhibits TGFB-induced EMT and promotes MET in primary human RPE cells
por: Hu, Xiaonan, et al.
Publicado: (2022)

miR-21 in Human Cardiomyopathies
por: Surina,, et al.
Publicado: (2021)

MiR-29a and MiR-140 Protect Chondrocytes against the Anti-Proliferation and Cell Matrix Signaling Changes by IL-1β
por: Li, Xianghui, et al.
Publicado: (2016)

Curcumin rescues breast cells from epithelial-mesenchymal transition and invasion induced by anti-miR-34a
por: Gallardo, Marcela, et al.
Publicado: (2019)

Bortezomib inhibits proliferation, migration, and TGF-β1–induced epithelial–mesenchymal transition of RPE cells
por: Moon, Kun, et al.
Publicado: (2017)

miR-21 Promotes Fibrogenic Epithelial-to-Mesenchymal Transition of Epicardial Mesothelial Cells Involving Programmed Cell Death 4 and Sprouty-1
por: Brønnum, Hasse, et al.
Publicado: (2013)

Lentiviral CRISPR/Cas9 vector mediated miR-21 gene editing inhibits the epithelial to mesenchymal transition in ovarian cancer cells
por: Huo, Wenying, et al.
Publicado: (2017)

Puerarin inhibits hepatocellular carcinoma invasion and metastasis through miR-21-mediated PTEN/AKT signaling to suppress the epithelial-mesenchymal transition
por: Zhou, Yuan, et al.
Publicado: (2020)

miR-300 inhibits epithelial to mesenchymal transition and metastasis by targeting Twist in human epithelial cancer
por: Yu, Jingshuang, et al.
Publicado: (2014)

Up-regulated miR-133a orchestrates epithelial-mesenchymal transition of airway epithelial cells
por: Chen, Linjie, et al.
Publicado: (2018)

Glioma stem cells-derived exosomes promote the angiogenic ability of endothelial cells through miR-21/VEGF signal
por: Sun, Xu, et al.
Publicado: (2017)

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels
por: Lee, Yang-ja, et al.
Publicado: (2018)

miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer
por: Hiramoto, Hidekazu, et al.
Publicado: (2017)

Regulation of cell growth and migration by miR-96 and miR-183 in a breast cancer model of epithelial-mesenchymal transition
por: Anderson, Olivia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_69qth0mantg0l65urmut043esh