Substantial heterogeneity of inflammatory cytokine production and its inhibition by a triple cocktail of toll-like receptor blockers in early sepsis

INTRODUCTION: Early sepsis is a life-threatening immune dysregulation believed to feature a “cytokine storm” due to activation of pattern recognition receptors by pathogen and danger associated molecular patterns. However, treatments with single toll-like receptor (TLR) blockers have shown no clinic...

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Detalles Bibliográficos
Autores principales: Buys, Willem, Bick, Alexandra, Madel, Rabea J., Westendorf, Astrid M., Buer, Jan, Herbstreit, Frank, Kirschning, Carsten J., Peters, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588698/
https://www.ncbi.nlm.nih.gov/pubmed/37869001
http://dx.doi.org/10.3389/fimmu.2023.1277033

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