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Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling

In toxicological concentration-response studies, a frequent goal is the determination of an ‘alert concentration’, i.e. the lowest concentration where a notable change in the response in comparison to the control is observed. In high-throughput gene expression experiments, e.g. based on microarray o...

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Detalles Bibliográficos
Autores principales: Kappenberg, Franziska, Rahnenführer, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588876/
https://www.ncbi.nlm.nih.gov/pubmed/37862297
http://dx.doi.org/10.1371/journal.pone.0293180