Cargando…
Information sharing in high-dimensional gene expression data for improved parameter estimation in concentration-response modelling
In toxicological concentration-response studies, a frequent goal is the determination of an ‘alert concentration’, i.e. the lowest concentration where a notable change in the response in comparison to the control is observed. In high-throughput gene expression experiments, e.g. based on microarray o...
Autores principales: | Kappenberg, Franziska, Rahnenführer, Jörg |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588876/ https://www.ncbi.nlm.nih.gov/pubmed/37862297 http://dx.doi.org/10.1371/journal.pone.0293180 |
Ejemplares similares
-
Benefit of using interaction effects for the analysis of high-dimensional time-response or dose-response data for two-group comparisons
por: Duda, Julia C., et al.
Publicado: (2023) -
Comparison of observation-based and model-based identification of alert concentrations from concentration–expression data
por: Kappenberg, Franziska, et al.
Publicado: (2021) -
Handling deviating control values in concentration-response curves
por: Kappenberg, Franziska, et al.
Publicado: (2020) -
Benchmark of filter methods for feature selection in high-dimensional gene expression survival data
por: Bommert, Andrea, et al.
Publicado: (2021) -
Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
por: Kappenberg, Franziska, et al.
Publicado: (2023)