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Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation

Scrub typhus is a mite-borne infectious disease endemic in India, Korea, China, Japan, Taiwan, Pakistan, Malaysia, Thailand, and Australia. It has a multitude of clinical manifestations ranging from mild symptoms like headache, myalgia, anorexia, fever, and rash to severe multiorgan failure. It can...

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Detalles Bibliográficos
Autores principales: Kamra, Namita, Jagadeesan, Subramani, Singh, Ramandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588906/
https://www.ncbi.nlm.nih.gov/pubmed/37868404
http://dx.doi.org/10.7759/cureus.45622
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author Kamra, Namita
Jagadeesan, Subramani
Singh, Ramandeep
author_facet Kamra, Namita
Jagadeesan, Subramani
Singh, Ramandeep
author_sort Kamra, Namita
collection PubMed
description Scrub typhus is a mite-borne infectious disease endemic in India, Korea, China, Japan, Taiwan, Pakistan, Malaysia, Thailand, and Australia. It has a multitude of clinical manifestations ranging from mild symptoms like headache, myalgia, anorexia, fever, and rash to severe multiorgan failure. It can also lead to several complications, including pancreatitis, hepatitis, myocardial infarction, and cerebral infarction. A few cases of splenic infarction are also reported. We report a rare case of a 40-year-old female presenting with fever and left upper quadrant abdominal pain of acute onset. She is diagnosed serologically with scrub typhus using enzyme-linked immunosorbent assay (ELISA) after ruling out other infectious causes, including other tropical diseases. Abdominal computed tomography revealed splenic infarction attributed to scrub typhus after excluding other etiologies. She improved after a course of doxycycline and was advised to follow up. Hence, a splenic infarct should be suspected in a patient with scrub typhus complaining of acute left hypochondriac pain.
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spelling pubmed-105889062023-10-21 Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation Kamra, Namita Jagadeesan, Subramani Singh, Ramandeep Cureus Internal Medicine Scrub typhus is a mite-borne infectious disease endemic in India, Korea, China, Japan, Taiwan, Pakistan, Malaysia, Thailand, and Australia. It has a multitude of clinical manifestations ranging from mild symptoms like headache, myalgia, anorexia, fever, and rash to severe multiorgan failure. It can also lead to several complications, including pancreatitis, hepatitis, myocardial infarction, and cerebral infarction. A few cases of splenic infarction are also reported. We report a rare case of a 40-year-old female presenting with fever and left upper quadrant abdominal pain of acute onset. She is diagnosed serologically with scrub typhus using enzyme-linked immunosorbent assay (ELISA) after ruling out other infectious causes, including other tropical diseases. Abdominal computed tomography revealed splenic infarction attributed to scrub typhus after excluding other etiologies. She improved after a course of doxycycline and was advised to follow up. Hence, a splenic infarct should be suspected in a patient with scrub typhus complaining of acute left hypochondriac pain. Cureus 2023-09-20 /pmc/articles/PMC10588906/ /pubmed/37868404 http://dx.doi.org/10.7759/cureus.45622 Text en Copyright © 2023, Kamra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Kamra, Namita
Jagadeesan, Subramani
Singh, Ramandeep
Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title_full Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title_fullStr Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title_full_unstemmed Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title_short Scrub Typhus Presenting As Acute Febrile Illness With Splenic Infarct: A Rare Manifestation
title_sort scrub typhus presenting as acute febrile illness with splenic infarct: a rare manifestation
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588906/
https://www.ncbi.nlm.nih.gov/pubmed/37868404
http://dx.doi.org/10.7759/cureus.45622
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