Accessible and Generalizable in Vitro Luminescence Assay for Detecting GPCR Activation

[Image: see text] G protein-coupled receptors (GPCRs) serve critical physiological roles as the most abundant family of receptors. Here, we describe the design of a generalizable and cell lysate-based method that leverages the interaction between an agonist-activated GPCR and a conformation-specific...

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Detalles Bibliográficos
Autores principales: Miller, Ruby M., Sescil, Jennifer, Sarcinella, Marina C., Bailey, Ryan C., Wang, Wenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588934/
https://www.ncbi.nlm.nih.gov/pubmed/37868356
http://dx.doi.org/10.1021/acsmeasuresciau.3c00021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588934/
https://www.ncbi.nlm.nih.gov/pubmed/37868356
http://dx.doi.org/10.1021/acsmeasuresciau.3c00021

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