Cargando…
Accessible and Generalizable in Vitro Luminescence Assay for Detecting GPCR Activation
[Image: see text] G protein-coupled receptors (GPCRs) serve critical physiological roles as the most abundant family of receptors. Here, we describe the design of a generalizable and cell lysate-based method that leverages the interaction between an agonist-activated GPCR and a conformation-specific...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10588934/ https://www.ncbi.nlm.nih.gov/pubmed/37868356 http://dx.doi.org/10.1021/acsmeasuresciau.3c00021 |